Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
---|---|---|---|---|---|---|---|---|
ELMI004828 | O00716 E2F3 E2F3_HUMAN |
442 | 450 | SLGEEEGISDLFDAYDLEKL | TP | --- | Homo sapiens (Human) | 465 |
Instance evidence
Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
---|---|---|---|---|---|---|---|
experimental | MI:0065 | isothermal titration calorimetry | in vitro | Liban,2016 | support | certain | InteractionDetection |
Interactions
Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
---|---|---|---|---|---|
(P06400) RB_HUMAN | IPR002720
(Retinoblastoma-associated protein A-box)
Retinoblastoma-like and retinoblastoma-associated proteins may have a function in cell cycle regulation |
373 | 573 | 1.2/1.2 | [mitab][xml] |
(P06400) RB_HUMAN | IPR002719
(Retinoblastoma-associated protein, B-box)
This entry includes retinoblastoma-associated protein (RB, also known as pRb, RB, p1051), retinoblastoma-like protein 1 (RBL1, also known as p107) and retinoblastoma-like protein 2 (RBL2, also kno... |
646 | 765 | [mitab][xml] | |
(P28749) RBL1_HUMAN | IPR002720
(Retinoblastoma-associated protein A-box)
Retinoblastoma-like and retinoblastoma-associated proteins may have a function in cell cycle regulation |
385 | 578 | 7.0/7.0 | [mitab][xml] |
(P28749) RBL1_HUMAN | IPR002719
(Retinoblastoma-associated protein, B-box)
This entry includes retinoblastoma-associated protein (RB, also known as pRb, RB, p1051), retinoblastoma-like protein 1 (RBL1, also known as p107) and retinoblastoma-like protein 2 (RBL2, also kno... |
787 | 943 | [mitab][xml] |
Pathways
KEGG: The sequence O00716 is implicated in the following 23 Pathways: (color codes: This sequence=red, interacting sequence=orange)- Bladder cancer
- Breast cancer
- Cell cycle
- Cellular senescence
- Chronic myeloid leukemia
- Cushing syndrome
- Endocrine resistance
- Epstein Barr virus infection
- Gastric cancer
- Glioma
- Hepatitis B
- Hepatitis C
- Hepatocellular carcinoma
- Human T cell leukemia virus 1 infection
- Human cytomegalovirus infection
- Kaposi sarcoma associated herpesvirus infection
- Melanoma
- MicroRNAs in cancer
- Non small cell lung cancer
- Pancreatic cancer
- Pathways in cancer
- Prostate cancer
- Small cell lung cancer
Please cite:
ELM-the Eukaryotic Linear Motif resource-2024 update.
(PMID:37962385)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement