The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003110 P03070 Large T antig
LT_SV40
101 119 ENLFCSEEMPSSDDEATADS TP 1GH6  
pdb:1GH6
Simian virus 40 708

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0096 pull down in vivo/in vitro support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Pilon,1996 support certain
experimental MI:1247 microscale thermophoresis in vitro Borchert,2014 support certain InteractionDetection
experimental MI:0065 isothermal titration calorimetry in vitro Singh,2005 support certain InteractionDetection
experimental MI:0114 x-ray crystallography in vitro Kim,2001 support certain InteractionDetection FeatureDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro DeCaprio,1988 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro DeCaprio,1988 support certain FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P06400) RB_HUMAN PF01857 (RB_B)
Retinoblastoma-associated protein B domain
646 765 0.44/0.44 [mitab][xml]
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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