The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI002215 P50542 PEX5
PEX5_HUMAN
159 163 LSVSPARWAEEYLEQSEEKL TP --- Homo sapiens (Human) 639

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0096 pull down in vivo/in vitro support certain InteractionDetection
experimental MI:0521 his tag in vivo/in vitro/in silico Otera,2002 support certain
predicted MI:0105 structure based prediction in silico Shiozawa,2009 support certain InteractionDetection
experimental MI:0016 circular dichroism in vitro Shiozawa,2009 support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Otera,2002 support certain
experimental MI:0005 alanine scanning in vivo/in vitro/in silico Otera,2002 support certain FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q92968) PEX13_HUMAN PF00018 (SH3_1)
SH3 domain
278 328 [mitab][xml]
(O75381) PEX14_HUMAN PF04695 (Pex14_N)
Peroxisomal membrane anchor protein (Pex14p) conserved region
24 135 [mitab][xml]

o  Pathways

KEGG: The sequence P50542 is implicated in the following 1 Pathway: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM 2016-data update and new functionality of the eukaryotic linear motif resource. (PMID:26615199)

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