The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI001565 Q8TBB1 LNX1
LNX1_HUMAN
178 185 LMTDEPGLDNPAYVSSAEDG TP --- Homo sapiens (Human) 728

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0096 pull down in vivo/in vitro support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Dho,1998 support certain
experimental MI:0053 fluorescence polarization spectroscopy in vitro Li,1998 support certain InteractionDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Dho,1998 support certain InteractionDetection
experimental MI:0018 two hybrid in vivo Dho,1998 support certain InteractionDetection
experimental MI:0405 competition binding in vitro Dho,1998 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P16554) NUMB_DROME PF00640 (PID)
Phosphotyrosine interaction domain (PTB/PID)
83 205 1.25/2.33 [mitab][xml]
(P49757) NUMB_HUMAN PF00640 (PID)
Phosphotyrosine interaction domain (PTB/PID)
39 172 [mitab][xml]
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

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