The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI001562 Q07954 LRP1
LRP1_HUMAN
4501 4508 DPDKPTNFTNPVYATLYMGG TP --- Homo sapiens (Human) 4544

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0096 pull down in vivo/in vitro support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Pietrzik,2004 support certain
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Pietrzik,2004 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Pietrzik,2004 support certain FeatureDetection
experimental MI:0074 mutation analysis in vivo/in vitro Su,2002 support certain FeatureDetection
experimental MI:0018 two hybrid in vivo Su,2002 support certain InteractionDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Su,2002 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(O00213) APBB1_HUMAN PF00640 (PID)
Phosphotyrosine interaction domain (PTB/PID)
[mitab][xml]
(Q9UBP9) GULP1_HUMAN PF00640 (PID)
Phosphotyrosine interaction domain (PTB/PID)
27 155 [mitab][xml]

o  Pathways

KEGG: The sequence Q07954 is implicated in the following 2 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

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