Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
---|---|---|---|---|---|---|---|---|
ELMI001554 | P26010 ITGB7 ITB7_HUMAN |
772 | 779 | QQLNWKQDSNPLYKSAITTT | TP | --- | Homo sapiens (Human) | 798 |
Instance evidence
Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
---|---|---|---|---|---|---|---|
experimental | MI:0005 | alanine scanning | in vivo/in vitro/in silico | Calderwood,2003 | support | certain | FeatureDetection |
experimental | MI:0107 | surface plasmon resonance | in vitro | Calderwood,2003 | support | certain | InteractionDetection FeatureDetection |
Interactions
Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
---|---|---|---|---|---|
(Q99704) DOK1_HUMAN | PF02174
(IRS)
PTB domain (IRS-1 type) |
151 | 254 | [mitab][xml] | |
(P49757) NUMB_HUMAN | PF00640
(PID)
Phosphotyrosine interaction domain (PTB/PID) |
39 | 172 | [mitab][xml] |
Pathways
KEGG: The sequence P26010 is implicated in the following 11 Pathways: (color codes: This sequence=red, interacting sequence=orange)- Arrhythmogenic right ventricular cardiomyopathy
- Cell adhesion molecules
- Dilated cardiomyopathy
- ECM receptor interaction
- Focal adhesion
- Human papillomavirus infection
- Hypertrophic cardiomyopathy
- Intestinal immune network for IgA production
- PI3K Akt signaling pathway
- Regulation of actin cytoskeleton
- Transcriptional misregulation in cancer
Please cite:
ELM-the Eukaryotic Linear Motif resource-2024 update.
(PMID:37962385)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement