The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI001553 P05556 ITGB1
777 784 MNAKWDTGENPIYKSAVTTV TP --- Homo sapiens (Human) 798

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0005 alanine scanning in vivo/in vitro/in silico Calderwood,2003 support certain FeatureDetection
experimental MI:0107 surface plasmon resonance in vitro Calderwood,2003 support certain InteractionDetection FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(O75553) DAB1_HUMAN PF00640 (PID)
Phosphotyrosine interaction domain (PTB/PID)
42 168 [mitab][xml]
(Q9Y490) TLN1_HUMAN PF02174 (IRS)
PTB domain (IRS-1 type)
310 401 [mitab][xml]

o  Pathways

KEGG: The sequence P05556 is implicated in the following 25 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The Eukaryotic Linear Motif resource: 2022 release. (PMID:34718738)

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