The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003531 Q99569 PKP4
PKP4_HUMAN
1190 1192 STKRPSYRAEQYPGSPDSWV TP --- Homo sapiens (Human) 1192

o  Instance evidence

Evidence classPSMI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0084 phage display Ivarsson,2014 support certain InteractionDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Ivarsson,2014 support likely InteractionDetection
experimental MI:0403 colocalization in vitro Ivarsson,2014 support likely
experimental MI:0053 fluorescence polarization spectroscopy in vitro Ivarsson,2014 support likely InteractionDetection
experimental MI:0084 phage display Ivarsson,2014 support likely InteractionDetection
experimental MI:0101 sequence based prediction in silico Guo,2012 support certain InteractionDetection
experimental MI:0018 two hybrid in vivo Guo,2012 support certain InteractionDetection
experimental MI:0107 surface plasmon resonance in vitro Jaulin-Bastard,2002 support certain InteractionDetection FeatureDetection
experimental MI:0040 electron microscopy in vivo/in vitro Jaulin-Bastard,2002 support certain InteractionDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Jaulin-Bastard,2002 support certain InteractionDetection
experimental MI:0096 pull down in vivo/in vitro Jaulin-Bastard,2002 support certain InteractionDetection
experimental MI:0018 two hybrid in vivo Jaulin-Bastard,2002 support certain InteractionDetection
experimental MI:0416 fluorescence microscopy Izawa,2002 support certain InteractionDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Izawa,2002 support certain InteractionDetection
experimental MI:0018 two hybrid in vivo Izawa,2002 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q96RT1) LAP2_HUMAN PF00595 (PDZ)
PDZ domain (Also known as DHR or GLGF)
1321 1407 8.8/8.8 [mitab][xml]
(P70587) LRRC7_RAT PF00595 (PDZ)
PDZ domain (Also known as DHR or GLGF)
1401 1485 [mitab][xml]
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

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