ELM - instance LIG_PDZ_Wminus1_1 in sequence Q811U3 at position 946

Instance

Accession	Acc. Gene-, Name	Start	End	Subsequence	Logic	PDB	Organism	Length
ELMI003525	Q811U3 Erc1 RB6I2_RAT	946	948	SNQTNHKPSPDQDEEEGIWA	TP	1ZUB	Rattus norvegicus (Norway rat)	948

Instance evidence

Evidence class	PSI-MI	Method	BioSource	PubMed	Logic	Reliability	Notes
experimental	MI:0007	anti tag coimmunoprecipitation	in vivo	Ohtsuka,2002	support	certain	InteractionDetection
experimental	MI:0096	pull down	in vivo/in vitro	Ohtsuka,2002	support	certain	InteractionDetection
experimental	MI:0007	anti tag coimmunoprecipitation	in vivo	Takao-Rikitsu,2004	support	certain	InteractionDetection
experimental	MI:0018	two hybrid	in vivo	Wang,2002	support	certain	InteractionDetection
experimental	MI:0096	pull down	in vivo/in vitro	Wang,2002	support	certain	InteractionDetection
experimental	MI:0074	mutation analysis	in vivo/in vitro	Wang,2002	support	certain	FeatureDetection
experimental	MI:0065	isothermal titration calorimetry	in vitro	Lu,2005	support	likely	InteractionDetection
experimental	MI:0077	nuclear magnetic resonance	in vitro	Lu,2005	support	likely	InteractionDetection FeatureDetection

Interactions

Uniprot Id	Domain family	Domain Start	Domain End	Affinity Min/Max (µMol)	Notes
(Q9JIR4) RIMS1_RAT	PF00595 (PDZ) PDZ domain (Also known as DHR or GLGF)	619	703	0.27/0.27	[mitab][xml]

Pathways

KEGG: The sequence Q811U3 is implicated in the following 1 Pathway: (color codes: This sequence=red, interacting sequence=orange)

Please cite: The Eukaryotic Linear Motif resource: 2022 release. (PMID:34718738)

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