The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003542 Q6VVB1 NHLRC1
NHLC1_HUMAN
393 395 SLLVLDTASHSIKVYKVDWG TP --- Homo sapiens (Human) 395

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0997 ubiquitinase assay in vitro Sharma,2012 support certain InteractionDetection
experimental MI:1220 tag visualisation by luciferase assay Sharma,2012 support certain ParticipantIdentification
experimental MI:0416 fluorescence microscopy Sharma,2012 support certain InteractionDetection
experimental MI:0018 two hybrid in vivo Sharma,2012 support certain InteractionDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Sharma,2012 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(O14641) DVL2_HUMAN PF00595 (PDZ)
PDZ domain (Also known as DHR or GLGF)
267 352 [mitab][xml]

o  Pathways

KEGG: The sequence Q6VVB1 is implicated in the following 1 Pathway: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM — the eukaryotic linear motif resource in 2020. (PMID:31680160)

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