The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003552 Q16513 PKN2
PKN2_HUMAN
982 984 ILSEEEQEMFRDFDYIADWC TP --- Homo sapiens (Human) 984

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Gross,2001 support certain InteractionDetection
experimental MI:0573 mutation disrupting interaction in vivo/in vitro Gross,2001 support certain
experimental MI:0018 two hybrid in vivo Gross,2001 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q12923) PTN13_HUMAN PF00595 (PDZ)
PDZ domain (Also known as DHR or GLGF)
1501 1585 [mitab][xml]

o  Pathways

KEGG: The sequence Q16513 is implicated in the following 3 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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