Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
---|---|---|---|---|---|---|---|---|
ELMI002430 | P97288-3 Htr4 5HT4R_MOUSE |
366 | 371 | NGSTHVLSFPLLFRNRPVPV | TP | --- | Mus musculus (House mouse) | 371 |
Instance evidence
Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
---|---|---|---|---|---|---|---|
experimental | MI:0004 | affinity chromatography technology | in vivo/in vitro | Joubert,2004 | support | certain | InteractionDetection |
experimental | MI:0663 | confocal microscopy | in vivo/in vitro | Joubert,2004 | support | certain | InteractionDetection |
experimental | MI:0074 | mutation analysis | in vivo/in vitro | Joubert,2004 | support | certain | FeatureDetection |
Interactions
Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
---|---|---|---|---|---|
(Q63ZW7) INADL_MOUSE | PF00595
(PDZ)
PDZ domain (Also known as DHR or GLGF) |
[mitab][xml] |
Switches
This ELM instance is part of the following 1 switching mechanism annotated at the switches.ELM resource:
-
SWTI000499:
Alternative splicing removes the PDZ-binding motif of Isoform 5-HT4(E) of 5-hydroxytryptamine receptor 4 (Htr4), abrogating binding to InaD-like protein (Inadl).
Please cite:
ELM-the Eukaryotic Linear Motif resource-2024 update.
(PMID:37962385)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement