The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI002261 P46937 YAP1
YAP1_HUMAN
499 504 DMESVLAATKLDKESFLTWL TP --- Homo sapiens (Human) 504

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0096 pull down in vivo/in vitro support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Mohler,1999 support certain
experimental MI:0573 mutation disrupting interaction in vivo/in vitro Mohler,1999 support certain
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Mohler,1999 support certain InteractionDetection
experimental MI:0403 colocalization in vitro Mohler,1999 support certain
experimental MI:0405 competition binding in vitro Mohler,1999 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Mohler,1999 support certain FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(O14745) NHRF1_HUMAN PF00595 (PDZ)
PDZ domain (Also known as DHR or GLGF)
[mitab][xml]

o  Pathways

KEGG: The sequence P46937 is implicated in the following 1 Pathway: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
feedback@elm.eu.org