The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI001599 P09619 PDGFRB
PGFRB_HUMAN
1101 1106 EQLPDSGCPAPRAEAEDSFL TP 1GQ5  
pdb:1GQ5
Homo sapiens (Human) 1106

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0047 far western blotting in vitro Karthikeyan,2002 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Karthikeyan,2002 support certain FeatureDetection
experimental MI:0114 x-ray crystallography in vitro Karthikeyan,2002 support certain InteractionDetection FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(O14745) NHRF1_HUMAN PF00595 (PDZ)
PDZ domain (Also known as DHR or GLGF)
[mitab][xml]

o  Switches



This ELM instance is part of the following 1 switching mechanism annotated at the switches.ELM resource:

o  Pathways

KEGG: The sequence P09619 is implicated in the following 17 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
feedback@elm.eu.org