The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI001614 Q12986 NFX1
NFX1_HUMAN
11 23 SGTFKFNTDAAEFIPQEKKN TP --- Homo sapiens (Human) 1120

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0096 pull down in vivo/in vitro support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Katzenellenbogen,2007 support certain
experimental MI:0096 pull down in vivo/in vitro support likely InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Katzenellenbogen,2007 support likely
experimental MI:0074 mutation analysis in vivo/in vitro Katzenellenbogen,2007 support likely FeatureDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Katzenellenbogen,2007 support likely InteractionDetection
experimental MI:0943 detection by mass spectrometry in vivo/in vitro Katzenellenbogen,2007 support likely InteractionDetection
experimental MI:0004 affinity chromatography technology in vivo/in vitro Katzenellenbogen,2007 support likely InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Katzenellenbogen,2007 support certain FeatureDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Katzenellenbogen,2007 support certain InteractionDetection
experimental MI:0943 detection by mass spectrometry in vivo/in vitro Katzenellenbogen,2007 support certain InteractionDetection
experimental MI:0004 affinity chromatography technology in vivo/in vitro Katzenellenbogen,2007 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P11940) PABP1_HUMAN PF00658 (PABP)
Poly-adenylate binding protein, unique domain
543 614 [mitab][xml]
(Q13310) PABP4_HUMAN PF00658 (PABP)
Poly-adenylate binding protein, unique domain
552 623 [mitab][xml]

o  Pathways

KEGG: The sequence Q12986 is implicated in the following 1 Pathway: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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