The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI001611 P50616 TOB1
TOB1_HUMAN
265 277 QKTSALSPNAKEFIFPNMQG TP --- Homo sapiens (Human) 345

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0096 pull down in vivo/in vitro support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Ezzeddine,2007 support certain
experimental MI:0007 anti tag coimmunoprecipitation in vivo Ezzeddine,2007 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Ezzeddine,2007 support certain FeatureDetection
experimental MI:0074 mutation analysis in vivo/in vitro Funakoshi,2007 support certain FeatureDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Funakoshi,2007 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Ruan,2010 support certain FeatureDetection
experimental MI:0065 isothermal titration calorimetry in vitro Ruan,2010 support certain InteractionDetection
experimental MI:0077 nuclear magnetic resonance in vitro Ruan,2010 support certain InteractionDetection FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P11940) PABP1_HUMAN PF00658 (PABP)
Poly-adenylate binding protein, unique domain
543 614 [mitab][xml]

o  Pathways

KEGG: The sequence P50616 is implicated in the following 1 Pathway: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

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