Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
---|---|---|---|---|---|---|---|---|
ELMI000783 | Q15596 NCOA2 NCOA2_HUMAN |
689 | 695 | LKEKHKILHRLLQDSSSPVD | TP |
1GWQ |
Homo sapiens (Human) | 1464 |
Instance evidence
Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
---|---|---|---|---|---|---|---|
experimental | MI:0114 | x-ray crystallography | in vitro | Warnmark,2002 | support | certain | InteractionDetection FeatureDetection |
experimental | MI:0004 | affinity chromatography technology | in vivo/in vitro | Voegel,1998 | support | certain | InteractionDetection |
experimental | MI:0074 | mutation analysis | in vivo/in vitro | Voegel,1998 | support | certain | FeatureDetection |
not annotated | not specified | not specified | not specified |
Switches
This ELM instance is part of the following 1 switching mechanism annotated at the switches.ELM resource:
-
SWTI000261:
Binding of the 24261" target="_blank">glucocorticoid ligand to the nuclear Glucocorticoid receptor (NR3C1) makes the binding site for the NRBOX motif of Nuclear receptor coactivator 2 (NCOA2) accessible.
Pathways
KEGG: The sequence Q15596 is implicated in the following 2 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite:
The Eukaryotic Linear Motif resource: 2022 release.
(PMID:34718738)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement