The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI004669 Q9H7Z3 NRDE2
NRDE2_HUMAN
163 169 AVTGETFRTDKKPDPANWEY TP 6IEH  
Homo sapiens (Human) 1164

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0114 x-ray crystallography in vitro Wang,2019 support certain InteractionDetection FeatureDetection
experimental MI:0074 mutation analysis in vivo/in vitro Wang,2019 support certain FeatureDetection
experimental MI:1088 phenotype-based detection assay Wang,2019 support certain InteractionDetection
experimental MI:0256 rna interference in vivo Wang,2019 support certain InteractionDetection
experimental MI:0506 over expressed level in vivo Wang,2019 support certain
experimental MI:0807 comigration in gel electrophoresis in vitro Wang,2019 support certain InteractionDetection
experimental MI:0096 pull down in vivo/in vitro Wang,2019 support certain InteractionDetection
experimental MI:0113 western blot in vitro Wang,2019 support certain ParticipantIdentification FeatureDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Wang,2019 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P42285) MTREX_HUMAN IPR025696 (rRNA-processing arch domain)
The essential RNA helicase Mtr4 is an exosome-activating cofactor
582 841 [mitab][xml]
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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