The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI004670 Q12476 AIR2
AIR2_YEAST
8 14 EKNTAPFVVDTAPTTPPDKL TP 4U4C  
Saccharomyces cerevisiae S288c 344

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0114 x-ray crystallography in vitro Falk,2014 support certain InteractionDetection FeatureDetection
experimental MI:0240 fusion protein in vivo/in vitro Falk,2014 support certain InteractionDetection ParticipantIdentification
experimental MI:0091 chromatography technology in vitro Falk,2014 support certain InteractionDetection
experimental MI:0096 pull down in vivo/in vitro Falk,2014 support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Falk,2014 support certain
experimental MI:0074 mutation analysis in vivo/in vitro Falk,2014 support certain FeatureDetection
experimental MI:0065 isothermal titration calorimetry in vitro Falk,2014 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P47047) MTR4_YEAST IPR025696 (rRNA-processing arch domain)
The essential RNA helicase Mtr4 is an exosome-activating cofactor
602 872 [mitab][xml]

o  Pathways

KEGG: The sequence Q12476 is implicated in the following 1 Pathway: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The Eukaryotic Linear Motif resource: 2022 release. (PMID:34718738)

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