The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI004756 Q9UQ84 EXO1
EXO1_HUMAN
791 800 GLQIKLNELWKNFGFKKDSE TP --- Homo sapiens (Human) 846

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0101 sequence based prediction in silico Guervilly,2022 support likely InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Guervilly,2022 support likely FeatureDetection
experimental MI:0096 pull down in vivo/in vitro Guervilly,2022 support likely InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P43246) MSH2_HUMAN IPR007696 (DNA mismatch repair protein MutS, core)
Mismatch repair contributes to the overall fidelity of DNA replication and is essential for combating the adverse effects of damage to the genome
305 645 [mitab][xml]

o  Pathways

KEGG: The sequence Q9UQ84 is implicated in the following 1 Pathway: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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