The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI004753 Q9NXL9 MCM9
MCM9_HUMAN
917 925 PPGSPVAKLAKFTFKQKSKL TP --- Homo sapiens (Human) 1143

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0256 rna interference in vivo Traver,2015 support likely InteractionDetection
experimental MI:1088 phenotype-based detection assay Traver,2015 support likely InteractionDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Traver,2015 support likely InteractionDetection
experimental MI:0943 detection by mass spectrometry in vivo/in vitro Traver,2015 support likely InteractionDetection
experimental MI:0004 affinity chromatography technology in vivo/in vitro Traver,2015 support likely InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P43246) MSH2_HUMAN IPR007696 (DNA mismatch repair protein MutS, core)
Mismatch repair contributes to the overall fidelity of DNA replication and is essential for combating the adverse effects of damage to the genome
305 645 [mitab][xml]
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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