The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI004751 O75717 WDHD1
WDHD1_HUMAN
1117 1126 QKPLDFSTNQKLSAFAFKQE TP --- Homo sapiens (Human) 1129

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:1088 phenotype-based detection assay Chen,2016 support certain InteractionDetection
experimental MI:0113 western blot in vitro Chen,2016 support certain ParticipantIdentification FeatureDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Chen,2016 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Chen,2016 support certain FeatureDetection
experimental MI:0096 pull down in vivo/in vitro Chen,2016 support certain InteractionDetection
experimental MI:0676 tandem affinity purification Chen,2016 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P43246) MSH2_HUMAN IPR007696 (DNA mismatch repair protein MutS, core)
Mismatch repair contributes to the overall fidelity of DNA replication and is essential for combating the adverse effects of damage to the genome
305 645 [mitab][xml]
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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