The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003321 O94907 DKK1
DKK1_HUMAN
37 43 ATLNSVLNSNAIKNLPPPLG TP 3SOQ  
Homo sapiens (Human) 266

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0074 mutation analysis in vivo/in vitro Bourhis,2011 support certain FeatureDetection
experimental MI:0114 x-ray crystallography in vitro Bourhis,2011 support certain InteractionDetection FeatureDetection
experimental MI:0411 elisa in vitro Bourhis,2011 support certain InteractionDetection ParticipantIdentification

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(O75581) LRP6_HUMAN PF00058 (Ldl_recept_b)
Low-density lipoprotein receptor repeat class B
6.0/6.0 [mitab][xml]

o  Pathways

KEGG: The sequence O94907 is implicated in the following 3 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM — the eukaryotic linear motif resource in 2020. (PMID:31680160)

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