The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI004448 Q9H6L5-1 RETREG1
RETR1_HUMAN
454 463 TEEGDDFELLDQSELDQIES TP 7BRQ  
Homo sapiens (Human) 497

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0074 mutation analysis in vivo/in vitro Mochida,2020 support certain FeatureDetection
experimental MI:0114 x-ray crystallography in vitro Mochida,2020 support certain InteractionDetection FeatureDetection
experimental MI:0033 deletion analysis Li,2018 support certain FeatureDetection
experimental MI:0065 isothermal titration calorimetry in vitro Li,2018 support certain InteractionDetection
experimental MI:0033 deletion analysis Mochida,2020 support certain FeatureDetection
experimental MI:0065 isothermal titration calorimetry in vitro Mochida,2020 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(O95166) GBRAP_HUMAN PF02991 (Atg8)
Autophagy protein Atg8 ubiquitin like
13 116 0.07/0.21 [mitab][xml]
(Q9H0R8) GBRL1_HUMAN PF02991 (Atg8)
Autophagy protein Atg8 ubiquitin like
13 116 0.08/0.16 [mitab][xml]
(P60520) GBRL2_HUMAN PF02991 (Atg8)
Autophagy protein Atg8 ubiquitin like
13 116 0.2/0.4 [mitab][xml]
(Q9H492) MLP3A_HUMAN PF02991 (Atg8)
Autophagy protein Atg8 ubiquitin like
15 120 0.18/0.24 [mitab][xml]
(Q9BXW4) MLP3C_HUMAN PF02991 (Atg8)
Autophagy protein Atg8 ubiquitin like
21 126 0.76/1.46 [mitab][xml]
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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