ELM - instance LIG_LIR_Gen_1 in sequence Q9BQS8 at position 1277

Instance

Accession	Acc. Gene-, Name	Start	End	Subsequence	Logic	PDB	Organism	Length
ELMI004477	Q9BQS8 FYCO1 FYCO1_HUMAN	1277	1288	RPPDDAVFDIITDEELCQIQ	TP	5CX3	Homo sapiens (Human)	1478

Instance evidence

Evidence class	PSI-MI	Method	BioSource	PubMed	Logic	Reliability	Notes
experimental	MI:0403	colocalization	in vitro	Cheng,2016	support	certain
experimental	MI:0074	mutation analysis	in vivo/in vitro	Cheng,2016	support	certain	FeatureDetection
experimental	MI:0077	nuclear magnetic resonance	in vitro	Cheng,2016	support	certain	InteractionDetection FeatureDetection
experimental	MI:0114	x-ray crystallography	in vitro	Cheng,2016	support	certain	InteractionDetection FeatureDetection
experimental	MI:0065	isothermal titration calorimetry	in vitro	Cheng,2016	support	certain	InteractionDetection
experimental	MI:0091	chromatography technology	in vitro	Cheng,2016	support	certain	InteractionDetection

Interactions

Uniprot Id	Domain family	Domain Start	Domain End	Affinity Min/Max (µMol)	Notes
(O95166) GBRAP_HUMAN	PF02991 (Atg8) Autophagy protein Atg8 ubiquitin like	13	116	2.88/3.94	[mitab][xml]
(Q9H0R8) GBRL1_HUMAN	PF02991 (Atg8) Autophagy protein Atg8 ubiquitin like	13	116	3.16/3.74	[mitab][xml]
(P60520) GBRL2_HUMAN	PF02991 (Atg8) Autophagy protein Atg8 ubiquitin like	13	116	202.0/262.0	[mitab][xml]
(Q9H492) MLP3A_HUMAN	PF02991 (Atg8) Autophagy protein Atg8 ubiquitin like	15	120	0.47/0.61	[mitab][xml]
(Q9GZQ8) MLP3B_HUMAN	PF02991 (Atg8) Autophagy protein Atg8 ubiquitin like	15	120	0.18/0.2	[mitab][xml]
(Q9BXW4) MLP3C_HUMAN	PF02991 (Atg8) Autophagy protein Atg8 ubiquitin like	21	126	2.33/2.81	[mitab][xml]

Pathways

KEGG: The sequence Q9BQS8 is implicated in the following 1 Pathway: (color codes: This sequence=red, interacting sequence=orange)

Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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