The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI004469 Q99442 SEC62
SEC62_HUMAN
362 371 SGNGNDFEMITKEELEQQTD TP 7BRT  
Homo sapiens (Human) 399

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0074 mutation analysis in vivo/in vitro Mochida,2020 support certain FeatureDetection
experimental MI:0114 x-ray crystallography in vitro Mochida,2020 support certain InteractionDetection FeatureDetection
experimental MI:0033 deletion analysis Mochida,2020 support certain FeatureDetection
experimental MI:0065 isothermal titration calorimetry in vitro Mochida,2020 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(O95166) GBRAP_HUMAN PF02991 (Atg8)
Autophagy protein Atg8 ubiquitin like
13 116 0.16/0.22 [mitab][xml]
(Q9H0R8) GBRL1_HUMAN PF02991 (Atg8)
Autophagy protein Atg8 ubiquitin like
13 116 0.336/0.444 [mitab][xml]
(P60520) GBRL2_HUMAN PF02991 (Atg8)
Autophagy protein Atg8 ubiquitin like
13 116 0.43/0.73 [mitab][xml]
(Q9H492) MLP3A_HUMAN PF02991 (Atg8)
Autophagy protein Atg8 ubiquitin like
15 120 0.8/1.04 [mitab][xml]
(Q9GZQ8) MLP3B_HUMAN PF02991 (Atg8)
Autophagy protein Atg8 ubiquitin like
15 120 3.02/3.72 [mitab][xml]
(Q9BXW4) MLP3C_HUMAN PF02991 (Atg8)
Autophagy protein Atg8 ubiquitin like
21 126 4.33/6.03 [mitab][xml]

o  Pathways

KEGG: The sequence Q99442 is implicated in the following 2 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The Eukaryotic Linear Motif resource: 2022 release. (PMID:34718738)

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