The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI004472 Q8NEB9 PIK3C3
PK3C3_HUMAN
248 258 SPILTSFELVKVPDPQMSME U --- Homo sapiens (Human) 887

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0114 x-ray crystallography in vitro Birgisdottir,2019 support not specified InteractionDetection FeatureDetection
experimental MI:0074 mutation analysis in vivo/in vitro Birgisdottir,2019 support not specified FeatureDetection
experimental MI:0081 peptide array Birgisdottir,2019 support not specified InteractionDetection
experimental MI:0096 pull down in vivo/in vitro Birgisdottir,2019 support not specified InteractionDetection
experimental MI:0969 biolayer interferometry Birgisdottir,2019 support not specified InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(O95166) GBRAP_HUMAN PF02991 (Atg8)
Autophagy protein Atg8 ubiquitin like
13 116 45.6/53.4 [mitab][xml]
(Q9H0R8) GBRL1_HUMAN PF02991 (Atg8)
Autophagy protein Atg8 ubiquitin like
13 116 57.7/72.3 [mitab][xml]
(Q9H492) MLP3A_HUMAN PF02991 (Atg8)
Autophagy protein Atg8 ubiquitin like
15 120 162.5/197.5 [mitab][xml]
(Q9GZQ8) MLP3B_HUMAN PF02991 (Atg8)
Autophagy protein Atg8 ubiquitin like
15 120 500.5/589.5 [mitab][xml]
(Q9BXW4) MLP3C_HUMAN PF02991 (Atg8)
Autophagy protein Atg8 ubiquitin like
21 126 122.8/147.2 [mitab][xml]

o  Pathways

KEGG: The sequence Q8NEB9 is implicated in the following 16 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM — the eukaryotic linear motif resource in 2020. (PMID:31680160)

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