Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
---|---|---|---|---|---|---|---|---|
ELMI004472 | Q8NEB9 PIK3C3 PK3C3_HUMAN |
248 | 258 | SPILTSFELVKVPDPQMSME | U | --- | Homo sapiens (Human) | 887 |
Instance evidence
Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
---|---|---|---|---|---|---|---|
experimental | MI:0114 | x-ray crystallography | in vitro | Birgisdottir,2019 | support | not specified | InteractionDetection FeatureDetection |
experimental | MI:0074 | mutation analysis | in vivo/in vitro | Birgisdottir,2019 | support | not specified | FeatureDetection |
experimental | MI:0081 | peptide array | Birgisdottir,2019 | support | not specified | InteractionDetection | |
experimental | MI:0096 | pull down | in vivo/in vitro | Birgisdottir,2019 | support | not specified | InteractionDetection |
experimental | MI:0969 | biolayer interferometry | Birgisdottir,2019 | support | not specified | InteractionDetection |
Interactions
Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
---|---|---|---|---|---|
(O95166) GBRAP_HUMAN | PF02991
(Atg8)
Autophagy protein Atg8 ubiquitin like |
13 | 116 | 45.6/53.4 | [mitab][xml] |
(Q9H0R8) GBRL1_HUMAN | PF02991
(Atg8)
Autophagy protein Atg8 ubiquitin like |
13 | 116 | 57.7/72.3 | [mitab][xml] |
(Q9H492) MLP3A_HUMAN | PF02991
(Atg8)
Autophagy protein Atg8 ubiquitin like |
15 | 120 | 162.5/197.5 | [mitab][xml] |
(Q9GZQ8) MLP3B_HUMAN | PF02991
(Atg8)
Autophagy protein Atg8 ubiquitin like |
15 | 120 | 500.5/589.5 | [mitab][xml] |
(Q9BXW4) MLP3C_HUMAN | PF02991
(Atg8)
Autophagy protein Atg8 ubiquitin like |
21 | 126 | 122.8/147.2 | [mitab][xml] |
Pathways
KEGG: The sequence Q8NEB9 is implicated in the following 16 Pathways: (color codes: This sequence=red, interacting sequence=orange)- Alzheimer disease
- Amyotrophic lateral sclerosis
- Apelin signaling pathway
- Autophagy animal
- Autophagy other
- Huntington disease
- Inositol phosphate metabolism
- Kaposi sarcoma associated herpesvirus infection
- Metabolic pathways
- Pathways of neurodegeneration multiple diseases
- Phagosome
- Phosphatidylinositol signaling system
- Salmonella infection
- Shigellosis
- Spinocerebellar ataxia
- Tuberculosis
Please cite:
ELM-the Eukaryotic Linear Motif resource-2024 update.
(PMID:37962385)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement