The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI004471 Q8IZQ1 WDFY3
WDFY3_HUMAN
3344 3351 LSLDEKDGFIFVNYSEGQTR TP 3WIM  
Homo sapiens (Human) 3526

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0096 pull down in vivo/in vitro Morozov,2014 support certain InteractionDetection
experimental MI:0065 isothermal titration calorimetry in vitro Morozov,2014 support certain InteractionDetection
experimental MI:0096 pull down in vivo/in vitro Ledesma-Amaro,2014 support certain InteractionDetection
experimental MI:0065 isothermal titration calorimetry in vitro Ledesma-Amaro,2014 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Lystad,2014 support certain FeatureDetection
experimental MI:0403 colocalization in vitro Lystad,2014 support certain
experimental MI:0114 x-ray crystallography in vitro Lystad,2014 support certain InteractionDetection FeatureDetection
experimental MI:0096 pull down in vivo/in vitro Lystad,2014 support certain InteractionDetection
experimental MI:0065 isothermal titration calorimetry in vitro Lystad,2014 support certain InteractionDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Lystad,2014 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(O95166) GBRAP_HUMAN PF02991 (Atg8)
Autophagy protein Atg8 ubiquitin like
13 116 0.297/0.357 [mitab][xml]
(Q9H0R8) GBRL1_HUMAN PF02991 (Atg8)
Autophagy protein Atg8 ubiquitin like
13 116 0.366/0.408 [mitab][xml]
(P60520) GBRL2_HUMAN PF02991 (Atg8)
Autophagy protein Atg8 ubiquitin like
13 116 0.752/0.99 [mitab][xml]
(Q9BXW4) MLP3C_HUMAN PF02991 (Atg8)
Autophagy protein Atg8 ubiquitin like
21 126 17.64/23.96 [mitab][xml]
Please cite: ELM — the eukaryotic linear motif resource in 2020. (PMID:31680160)

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