The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI004447 O95197 RTN3
RTN3_HUMAN
246 256 DSPESPFEVIIDKAAFDKEF TP 7BRU  
Homo sapiens (Human) 1032

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0074 mutation analysis in vivo/in vitro Mochida,2020 support certain FeatureDetection
experimental MI:0114 x-ray crystallography in vitro Mochida,2020 support certain InteractionDetection FeatureDetection
experimental MI:0033 deletion analysis Mochida,2020 support certain FeatureDetection
experimental MI:0065 isothermal titration calorimetry in vitro Mochida,2020 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(O95166) GBRAP_HUMAN PF02991 (Atg8)
Autophagy protein Atg8 ubiquitin like
13 116 4.56/5.5 [mitab][xml]
(Q9H0R8) GBRL1_HUMAN PF02991 (Atg8)
Autophagy protein Atg8 ubiquitin like
13 116 4.49/5.51 [mitab][xml]
(P60520) GBRL2_HUMAN PF02991 (Atg8)
Autophagy protein Atg8 ubiquitin like
13 116 10.94/23.78 [mitab][xml]
(Q9H492) MLP3A_HUMAN PF02991 (Atg8)
Autophagy protein Atg8 ubiquitin like
15 120 13.19/21.17 [mitab][xml]
(Q9GZQ8) MLP3B_HUMAN PF02991 (Atg8)
Autophagy protein Atg8 ubiquitin like
15 120 19.52/38.12 [mitab][xml]

o  Pathways

KEGG: The sequence O95197 is implicated in the following 1 Pathway: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM — the eukaryotic linear motif resource in 2020. (PMID:31680160)

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