The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI004481 O75385 ULK1
ULK1_HUMAN
356 365 SCDTDDFVMVPAQFPGDLVA TP 6HYO  
Homo sapiens (Human) 1050

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0074 mutation analysis in vivo/in vitro Wirth,2019 support certain FeatureDetection
experimental MI:0114 x-ray crystallography in vitro Wirth,2019 support certain InteractionDetection FeatureDetection
experimental MI:0081 peptide array Wirth,2019 support certain InteractionDetection
experimental MI:0969 biolayer interferometry Wirth,2019 support certain InteractionDetection
experimental MI:0113 western blot in vitro Wirth,2019 support certain ParticipantIdentification FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(O95166) GBRAP_HUMAN PF02991 (Atg8)
Autophagy protein Atg8 ubiquitin like
13 116 0.046/0.054 [mitab][xml]
(Q9H0R8) GBRL1_HUMAN PF02991 (Atg8)
Autophagy protein Atg8 ubiquitin like
13 116 0.044/0.052 [mitab][xml]
(P60520) GBRL2_HUMAN PF02991 (Atg8)
Autophagy protein Atg8 ubiquitin like
13 116 0.48/0.58 [mitab][xml]
(Q9H492) MLP3A_HUMAN PF02991 (Atg8)
Autophagy protein Atg8 ubiquitin like
15 120 5.8/6.0 [mitab][xml]
(Q9GZQ8) MLP3B_HUMAN PF02991 (Atg8)
Autophagy protein Atg8 ubiquitin like
15 120 41.8/54.6 [mitab][xml]
(Q9BXW4) MLP3C_HUMAN PF02991 (Atg8)
Autophagy protein Atg8 ubiquitin like
21 126 2.2/2.8 [mitab][xml]

o  Pathways

KEGG: The sequence O75385 is implicated in the following 10 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM — the eukaryotic linear motif resource in 2020. (PMID:31680160)

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