The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI004455 O75143 ATG13
ATG13_HUMAN
443 452 GNTHDDFVMIDFKPAFSKDD TP --- Homo sapiens (Human) 517

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0074 mutation analysis in vivo/in vitro Suzuki,2014 support certain FeatureDetection
experimental MI:0107 surface plasmon resonance in vitro Suzuki,2014 support certain InteractionDetection FeatureDetection
experimental MI:0033 deletion analysis Suzuki,2014 support certain FeatureDetection
experimental MI:0096 pull down in vivo/in vitro Suzuki,2014 support certain InteractionDetection
experimental MI:0018 two hybrid in vivo Suzuki,2014 support certain InteractionDetection
experimental MI:0113 western blot in vitro Wirth,2019 support certain ParticipantIdentification FeatureDetection
experimental MI:0969 biolayer interferometry Wirth,2019 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(O95166) GBRAP_HUMAN PF02991 (Atg8)
Autophagy protein Atg8 ubiquitin like
13 116 0.55/0.63 [mitab][xml]
(Q9H0R8) GBRL1_HUMAN PF02991 (Atg8)
Autophagy protein Atg8 ubiquitin like
13 116 0.49/0.57 [mitab][xml]
(P60520) GBRL2_HUMAN PF02991 (Atg8)
Autophagy protein Atg8 ubiquitin like
13 116 2.9/3.3 [mitab][xml]
(Q9H492) MLP3A_HUMAN PF02991 (Atg8)
Autophagy protein Atg8 ubiquitin like
15 120 3.8/4.4 [mitab][xml]
(Q9GZQ8) MLP3B_HUMAN PF02991 (Atg8)
Autophagy protein Atg8 ubiquitin like
15 120 47.0/53.0 [mitab][xml]
(Q9BXW4) MLP3C_HUMAN PF02991 (Atg8)
Autophagy protein Atg8 ubiquitin like
21 126 0.44/0.52 [mitab][xml]

o  Pathways

KEGG: The sequence O75143 is implicated in the following 8 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM — the eukaryotic linear motif resource in 2020. (PMID:31680160)

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