The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI004530 Q15648 MED1
MED1_HUMAN
878 898 FGEEYFDESSQSGDNDDFKGF TP --- Homo sapiens (Human) 1581

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0077 nuclear magnetic resonance in vitro Sharma,2018 support certain InteractionDetection FeatureDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Sharma,2018 support certain InteractionDetection
experimental MI:0905 amplified luminescent proximity homogeneous assay Sharma,2018 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Sharma,2018 support certain FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(O75475) PSIP1_HUMAN IPR021567 (Lens epithelium-derived growth factor, integrase-binding domain)
Lens epithelium-derived growth factor (LEDGF), also known as transcriptional co-activator p75, is a chromatin-associated protein that protects cells from stress-induced apoptosis
349 449 254.0/284.0 [mitab][xml]

o  Pathways

KEGG: The sequence Q15648 is implicated in the following 2 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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