The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI002925 Q8IWE5 PLEKHM2
PKHM2_HUMAN
234 241 VPSVPSTDWEDGDLTDTVSG TP --- Homo sapiens (Human) 1019

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0663 confocal microscopy in vivo/in vitro Rosa-Ferreira,2011 support likely InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Rosa-Ferreira,2011 support likely FeatureDetection
experimental MI:0096 pull down in vivo/in vitro Dodding,2011 support likely InteractionDetection
experimental MI:0416 fluorescence microscopy Dodding,2011 support likely InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Dodding,2011 support likely FeatureDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Dodding,2011 support likely InteractionDetection
experimental MI:0053 fluorescence polarization spectroscopy in vitro Pernigo,2013 support certain InteractionDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Pernigo,2013 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(O88447) KLC1_MOUSE SM00028 (TPR)
Tetratricopeptide repeats.
253 286 [mitab][xml]
(O88448) KLC2_MOUSE SM00028 (TPR)
Tetratricopeptide repeats.
239 272 111.0/111.0 [mitab][xml]
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

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