The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI004156 O25272 HP_0539
O25272_HELPY
76 82 KAAIALRGDLALLKANFEAN TP --- Helicobacter pylori 26695 237

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:1088 phenotype-based detection assay Barden,2015 support certain InteractionDetection
experimental MI:0411 elisa in vitro Barden,2015 support certain InteractionDetection ParticipantIdentification
experimental MI:0074 mutation analysis in vivo/in vitro Barden,2015 support certain FeatureDetection
experimental MI:0411 elisa in vitro Buss,2019 support certain InteractionDetection ParticipantIdentification
experimental MI:0053 fluorescence polarization spectroscopy in vitro Buss,2019 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Buss,2019 support certain FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P08648) ITA5_HUMAN PF01839 (FG-GAP)
FG-GAP repeat
326 368 [mitab][xml]
(P06756) ITAV_HUMAN PF01839 (FG-GAP)
FG-GAP repeat
252 286 0.023/0.07 [mitab][xml]
(P05556) ITB1_HUMAN PF00362 (Integrin_beta)
Integrin, beta chain
138 382 [mitab][xml]
(P05106) ITB3_HUMAN PF00362 (Integrin_beta)
Integrin, beta chain
133 381 [mitab][xml]
(P18084) ITB5_HUMAN PF00362 (Integrin_beta)
Integrin, beta chain
133 382 [mitab][xml]
(P18564) ITB6_HUMAN PF00362 (Integrin_beta)
Integrin, beta chain
128 375 0.023/0.07 [mitab][xml]
(P26012) ITB8_HUMAN PF00362 (Integrin_beta)
Integrin, beta chain
142 388 [mitab][xml]
Please cite: ELM — the eukaryotic linear motif resource in 2020. (PMID:31680160)

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