The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI004660 Q13568 IRF5
IRF5_HUMAN
441 446 LSWSADSIRLQISNPDLKDR TP 3DSH  
Homo sapiens (Human) 498

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0027 cosedimentation in vitro Chen,2008 support certain InteractionDetection
experimental MI:0071 molecular sieving in vivo/in vitro Chen,2008 support certain InteractionDetection
experimental MI:0065 isothermal titration calorimetry in vitro Chen,2008 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Chen,2008 support certain FeatureDetection
experimental MI:0114 x-ray crystallography in vitro Chen,2008 support certain InteractionDetection FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q13568) IRF5_HUMAN IPR019471 (Interferon regulatory factor-3)
This is the interferon-regulatory factor 3 chain of the hetero-dimeric structure which also contains the shorter chain CREB-binding protein
247 431 [mitab][xml]
Please cite: The Eukaryotic Linear Motif resource: 2022 release. (PMID:34718738)

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