The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003497 C6UYL8 tir
TIR_ECO5T
456 458 TSSIGTVQNPYADVKTSLHD TP 2YKT  
Escherichia coli O157:H7 str. TW14359 558

o  Instance evidence

Evidence classPSMI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0010 beta galactosidase complementation Vingadassalom,2009 support certain InteractionDetection
experimental MI:1088 phenotype-based detection assay Vingadassalom,2009 support certain InteractionDetection
experimental MI:0005 alanine scanning in vivo/in vitro/in silico Vingadassalom,2009 support certain FeatureDetection
experimental MI:0018 two hybrid in vivo Vingadassalom,2009 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Vingadassalom,2009 support certain FeatureDetection
experimental MI:0427 Identification by mass spectrometry Weiss,2009 support certain ParticipantIdentification
experimental MI:0096 pull down in vivo/in vitro Weiss,2009 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Weiss,2009 support certain FeatureDetection
experimental MI:1088 phenotype-based detection assay Campellone,2006 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Campellone,2006 support certain FeatureDetection
experimental MI:0096 pull down in vivo/in vitro de Groot,2011 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro de Groot,2011 support certain FeatureDetection
experimental MI:0114 x-ray crystallography in vitro de Groot,2011 support certain InteractionDetection FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q9UQB8) BAIP2_HUMAN PF08397 (IMD)
IRSp53/MIM homology domain
17 237 49.0/69.0 [mitab][xml]
(Q9UHR4) BI2L1_HUMAN PF08397 (IMD)
IRSp53/MIM homology domain
16 236 [mitab][xml]
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

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