The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI001521 Q01094 E2F1
E2F1_HUMAN
97 100 KRRLDLETDHQYLAESSGPA TP --- Homo sapiens (Human) 437

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Knez,2006 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Tyagi,2007 support certain FeatureDetection
experimental MI:0018 two hybrid in vivo Tyagi,2007 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P51610) HCFC1_HUMAN PF13415 (Kelch_3)
Galactose oxidase, central domain
91 145 [mitab][xml]
(P51610) HCFC1_HUMAN PF13415 (Kelch_3)
Galactose oxidase, central domain
146 208 [mitab][xml]
(P51610) HCFC1_HUMAN PF13415 (Kelch_3)
Galactose oxidase, central domain
215 263 [mitab][xml]
(P51610) HCFC1_HUMAN PF13415 (Kelch_3)
Galactose oxidase, central domain
264 330 [mitab][xml]

o  Pathways

KEGG: The sequence Q01094 is implicated in the following 26 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The Eukaryotic Linear Motif resource: 2022 release. (PMID:34718738)

ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
feedback@elm.eu.org