The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI001526 O43889 CREB3
CREB3_HUMAN
78 81 SNPCLVHHDHTYSLPRETVS TP --- Homo sapiens (Human) 395

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0096 pull down in vivo/in vitro support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Lu,1998 support certain
experimental MI:0018 two hybrid in vivo Lu,1998 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Lu,1998 support certain FeatureDetection
experimental MI:0074 mutation analysis in vivo/in vitro Freiman,1997 support certain FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P51610) HCFC1_HUMAN PF13415 (Kelch_3)
Galactose oxidase, central domain
91 145 [mitab][xml]
(P51610) HCFC1_HUMAN PF13415 (Kelch_3)
Galactose oxidase, central domain
146 208 [mitab][xml]
(P51610) HCFC1_HUMAN PF13415 (Kelch_3)
Galactose oxidase, central domain
215 263 [mitab][xml]
(P51610) HCFC1_HUMAN PF13415 (Kelch_3)
Galactose oxidase, central domain
264 330 [mitab][xml]

o  Pathways

KEGG: The sequence O43889 is implicated in the following 21 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

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