The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI002906 O75581 LRP6
LRP6_HUMAN
1604 1609 ERSYSHHLYPPPPSPCTDSS TP --- Homo sapiens (Human) 1613

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0573 mutation disrupting interaction in vivo/in vitro Tamai,2004 support certain
experimental MI:0005 alanine scanning in vivo/in vitro/in silico Tamai,2004 support certain FeatureDetection
experimental MI:0074 mutation analysis in vivo/in vitro Tamai,2004 support certain FeatureDetection
experimental MI:0114 x-ray crystallography in vitro Tamai,2004 support certain InteractionDetection FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P49840) GSK3A_HUMAN PF00069 (Pkinase)
Protein kinase domain
119 403 [mitab][xml]
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

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