Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
---|---|---|---|---|---|---|---|---|
ELMI002904 | O75581 LRP6 LRP6_HUMAN |
1569 | 1574 | YDSEPVPPPPTPRSQYLSAE | TP | --- | Homo sapiens (Human) | 1613 |
Instance evidence
Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
---|---|---|---|---|---|---|---|
experimental | MI:0573 | mutation disrupting interaction | in vivo/in vitro | Tamai,2004 | support | certain | |
experimental | MI:0005 | alanine scanning | in vivo/in vitro/in silico | Tamai,2004 | support | certain | FeatureDetection |
experimental | MI:0074 | mutation analysis | in vivo/in vitro | Tamai,2004 | support | certain | FeatureDetection |
experimental | MI:0114 | x-ray crystallography | in vitro | Tamai,2004 | support | certain | InteractionDetection FeatureDetection |
Interactions
Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
---|---|---|---|---|---|
(P49840) GSK3A_HUMAN | PF00069
(Pkinase)
Protein kinase domain |
119 | 403 | [mitab][xml] |
Pathways
KEGG: The sequence O75581 is implicated in the following 9 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite:
The Eukaryotic Linear Motif resource: 2022 release.
(PMID:34718738)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement