The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003671 O75084 FZD7
FZD7_HUMAN
547 557 TTGFWIWSGKTLQSWRRFYH TP --- Homo sapiens (Human) 574

o  Instance evidence

Evidence classPSMI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0016 circular dichroism in vitro Punchihewa,2009 support certain InteractionDetection
experimental MI:0405 competition binding in vitro Punchihewa,2009 support certain InteractionDetection
experimental MI:0005 alanine scanning in vivo/in vitro/in silico Punchihewa,2009 support certain FeatureDetection
experimental MI:0405 competition binding in vitro Wong,2003 support certain InteractionDetection
experimental MI:0051 fluorescence technology Wong,2003 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Wong,2003 support certain FeatureDetection
experimental MI:0096 pull down in vivo/in vitro Wong,2003 support certain InteractionDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Wong,2003 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(O14640) DVL1_HUMAN PF00595 (PDZ)
PDZ domain (Also known as DHR or GLGF)
251 336 [mitab][xml]
(P51141) DVL1_MOUSE PF00595 (PDZ)
PDZ domain (Also known as DHR or GLGF)
251 336 10.0/10.0 [mitab][xml]
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

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