The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003670 O42579 fzd3
FZD3_XENLA
496 506 PSVFWVGSKKTCFEWASFFH TP --- Xenopus laevis (African clawed frog) 664

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0663 confocal microscopy in vivo/in vitro Umbhauer,2000 support certain InteractionDetection
experimental MI:0113 western blot in vitro Umbhauer,2000 support certain ParticipantIdentification FeatureDetection
experimental MI:0074 mutation analysis in vivo/in vitro Umbhauer,2000 support certain FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P51142) DVL2_XENLA PF00595 (PDZ)
PDZ domain (Also known as DHR or GLGF)
254 339 [mitab][xml]

o  Pathways

KEGG: The sequence O42579 is implicated in the following 3 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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