Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
---|---|---|---|---|---|---|---|---|
ELMI000985 | Q13426 XRCC4 XRCC4_HUMAN |
231 | 237 | RDPVYDESTDEESENQTDLS | TP | --- | Homo sapiens (Human) | 336 |
Instance evidence
Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
---|---|---|---|---|---|---|---|
experimental | MI:0074 | mutation analysis | in vivo/in vitro | Koch,2004 | support | certain | FeatureDetection |
experimental | MI:0519 | glutathione s tranferase tag | in vitro | Koch,2004 | support | certain | |
experimental | MI:0065 | isothermal titration calorimetry | in vitro | Koch,2004 | support | certain | InteractionDetection |
experimental | MI:0053 | fluorescence polarization spectroscopy | in vitro | Koch,2004 | support | certain | InteractionDetection |
Switches
This ELM instance is part of the following 1 switching mechanism annotated at the switches.ELM resource:
-
SWTI000131:
Phosphorylation of T233 in the FHA-binding motif of DNA repair protein XRCC4 (XRCC4) by Casein kinase II subunit alpha (CSNK2A1) induces binding to the Bifunctional polynucleotide phosphatase/kinase (PNKP) protein.
Pathways
KEGG: The sequence Q13426 is implicated in the following 1 Pathway: (color codes: This sequence=red, interacting sequence=orange)
Please cite:
The Eukaryotic Linear Motif resource: 2022 release.
(PMID:34718738)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement