The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI001706 Q8TF74 WIPF2
WIPF2_HUMAN
400 412 ESKYSFHPVEDFPAPEEYKH TP --- Homo sapiens (Human) 440

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0096 pull down in vivo/in vitro support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Aspenstrom,2004 support certain
experimental MI:0113 western blot in vitro Aspenstrom,2004 support certain ParticipantIdentification FeatureDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Aspenstrom,2004 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Aspenstrom,2004 support certain FeatureDetection
experimental MI:0005 alanine scanning in vivo/in vitro/in silico Aspenstrom,2004 support certain FeatureDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Aspenstrom,2002 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Aspenstrom,2002 support certain FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P42768) WASP_HUMAN PF00568 (WH1)
WH1 domain
36 145 [mitab][xml]

o  Pathways

KEGG: The sequence Q8TF74 is implicated in the following 3 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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