ELM - instance LIG_EVH1_3 in sequence O43516 at position 454

Instance

Accession	Acc. Gene-, Name	Start	End	Subsequence	Logic	PDB	Organism	Length
ELMI001705	O43516 WIPF1 WIPF1_HUMAN	454	466	ESRFYFHPISDLPPPEPYVQ	TP	1MKE	Homo sapiens (Human)	503

Instance evidence

Evidence class	PSI-MI	Method	BioSource	PubMed	Logic	Reliability	Notes
experimental	MI:0113	western blot	in vitro	Volkman,2002	support	certain	ParticipantIdentification FeatureDetection
experimental	MI:0077	nuclear magnetic resonance	in vitro	Volkman,2002	support	certain	InteractionDetection FeatureDetection
experimental	MI:0074	mutation analysis	in vivo/in vitro	Volkman,2002	support	certain	FeatureDetection
experimental	MI:0105	structure based prediction	in silico	Volkman,2002	support	certain	InteractionDetection
experimental	MI:0074	mutation analysis	in vivo/in vitro	Peterson,2007	support	certain	FeatureDetection
experimental	MI:0077	nuclear magnetic resonance	in vitro	Peterson,2007	support	certain	InteractionDetection FeatureDetection
experimental	MI:0105	structure based prediction	in silico	Peterson,2007	support	certain	InteractionDetection
experimental	MI:0005	alanine scanning	in vivo/in vitro/in silico	Peterson,2007	support	certain	FeatureDetection
experimental	MI:0367	green fluorescent protein tag	in vivo	Zettl,2002	support	certain
experimental	MI:0005	alanine scanning	in vivo/in vitro/in silico	Zettl,2002	support	certain	FeatureDetection
experimental	MI:0074	mutation analysis	in vivo/in vitro	Zettl,2002	support	certain	FeatureDetection
experimental	MI:0096	pull down	in vivo/in vitro	Zettl,2002	support	certain	InteractionDetection

Interactions

Uniprot Id	Domain family	Domain Start	Domain End	Affinity Min/Max (µMol)	Notes
(O08816) WASL_RAT	PF00568 (WH1) WH1 domain	28	135		[mitab][xml]

Pathways

KEGG: The sequence O43516 is implicated in the following 3 Pathways: (color codes: This sequence=red, interacting sequence=orange)

Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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