The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI001705 O43516 WIPF1
WIPF1_HUMAN
454 466 ESRFYFHPISDLPPPEPYVQ TP 1MKE  
pdb:1MKE
Homo sapiens (Human) 503

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0113 western blot in vitro Volkman,2002 support certain ParticipantIdentification FeatureDetection
experimental MI:0077 nuclear magnetic resonance in vitro Volkman,2002 support certain InteractionDetection FeatureDetection
experimental MI:0074 mutation analysis in vivo/in vitro Volkman,2002 support certain FeatureDetection
experimental MI:0105 structure based prediction in silico Volkman,2002 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Peterson,2007 support certain FeatureDetection
experimental MI:0077 nuclear magnetic resonance in vitro Peterson,2007 support certain InteractionDetection FeatureDetection
experimental MI:0105 structure based prediction in silico Peterson,2007 support certain InteractionDetection
experimental MI:0005 alanine scanning in vivo/in vitro/in silico Peterson,2007 support certain FeatureDetection
experimental MI:0367 green fluorescent protein tag in vivo Zettl,2002 support certain
experimental MI:0005 alanine scanning in vivo/in vitro/in silico Zettl,2002 support certain FeatureDetection
experimental MI:0074 mutation analysis in vivo/in vitro Zettl,2002 support certain FeatureDetection
experimental MI:0096 pull down in vivo/in vitro Zettl,2002 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(O08816) WASL_RAT PF00568 (WH1)
WH1 domain
28 135 [mitab][xml]

o  Pathways

KEGG: The sequence O43516 is implicated in the following 1 Pathway: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

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