The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI002581 Q702N8 XIRP1
XIRP1_HUMAN
22 26 RMATAEDLPLPPPPALEDLP TP --- Homo sapiens (Human) 1843

o  Instance evidence

Evidence classPSMI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0081 peptide array van der Ven,2006 support certain InteractionDetection
experimental MI:0047 far western blotting in vitro van der Ven,2006 support certain InteractionDetection
experimental MI:0018 two hybrid in vivo van der Ven,2006 support certain InteractionDetection
experimental MI:0403 colocalization in vitro van der Ven,2006 support certain
experimental MI:0074 mutation analysis in vivo/in vitro van der Ven,2006 support certain FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q8N8S7) ENAH_HUMAN PF00568 (WH1)
WH1 domain
1 108 [mitab][xml]
(Q9UI08) EVL_HUMAN PF00568 (WH1)
WH1 domain
1 109 [mitab][xml]
(P50552) VASP_HUMAN PF00568 (WH1)
WH1 domain
1 110 [mitab][xml]

o  Switches



This ELM instance is part of the following 2 switching mechanisms annotated at the switches.ELM resource:
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
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