The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI000940 Q02548 PAX5
PAX5_HUMAN
178 186 DSAGSSYSISGILGITSPSA TP --- Homo sapiens (Human) 391

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0096 pull down in vivo/in vitro support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Eberhard,2000 support certain
experimental MI:0074 mutation analysis in vivo/in vitro Eberhard,2000 support certain FeatureDetection

o  Pathways

KEGG: The sequence Q02548 is implicated in the following 1 Pathway: (color codes: This sequence=red, interacting sequence=orange)

o  Diseases

  • Sequence Variation VAR_070682 (Pos 183) has been implicated in Leukemia, Acute Lymphoblastic; All (OMIM:613065).
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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