The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI004819 O75362 ZNF217
ZN217_HUMAN
752 760 SLLRSRRTGCPPALLGKDVP TP --- Homo sapiens (Human) 1048

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0007 anti tag coimmunoprecipitation in vivo Quinlan,2006 support certain InteractionDetection
experimental MI:0018 two hybrid in vivo Quinlan,2006 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Quinlan,2006 support certain FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P56546) CTBP2_MOUSE IPR006140 (D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain)
A number of NAD-dependent 2-hydroxyacid dehydrogenases which seem to be specific for the D-isomer of their substrate have been shown to be functionally and structurally related
140 323 [mitab][xml]
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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