The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI000453 P49418 AMPH
AMPH_HUMAN
380 385 HSPMSQTLPWDLWTTSTDLV TP 1UTC  
pdb:1UTC
Homo sapiens (Human) 695

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0096 pull down in vivo/in vitro support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Slepnev,2000 support certain
experimental MI:0096 pull down in vivo/in vitro support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Miele,2004 support certain
experimental MI:0096 pull down in vivo/in vitro support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Drake,2001 support certain
experimental MI:0113 western blot in vitro Drake,2001 support certain ParticipantIdentification FeatureDetection
experimental MI:0074 mutation analysis in vivo/in vitro Drake,2001 support certain FeatureDetection
experimental MI:0114 x-ray crystallography in vitro Miele,2004 support certain InteractionDetection FeatureDetection
experimental MI:0017 classical fluorescence spectroscopy in vitro Miele,2004 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Slepnev,2000 support certain FeatureDetection

o  Switches



This ELM instance is part of the following 2 switching mechanisms annotated at the switches.ELM resource:

o  Pathways

KEGG: The sequence P49418 is implicated in the following 2 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

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