The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI002957 P46531 NOTCH1
NOTC1_HUMAN
1767 1770 KRRRQHGQLWFPEGFKVSEA TP --- Homo sapiens (Human) 2555

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
predicted MI:0019 coimmunoprecipitation in vivo/in vitro Johnson,2010 support likely InteractionDetection
predicted MI:0065 isothermal titration calorimetry in vitro Johnson,2010 support likely InteractionDetection
predicted MI:0114 x-ray crystallography in vitro Johnson,2010 support likely InteractionDetection FeatureDetection
predicted MI:0363 inferred by author in silico Wilson,2006 support likely InteractionDetection ParticipantIdentification FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q06330) SUH_HUMAN PF09270 (BTD)
Beta-trefoil DNA-binding domain
179 328 0.068/0.076 [mitab][xml]

o  Pathways

KEGG: The sequence P46531 is implicated in the following 5 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

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